Know PK Deficiency

PK deficiency is an underdiagnosed cause of chronic hereditary hemolytic anemia, resulting from insufficient activity of the enzyme pyruvate kinase (PK). Do you have any patients with hemolytic anemia of unknown cause?
It could be PK deficiency.

Learn More
PK Deficiency Status Report

A 2015 article by Rachel Grace and colleagues reviews the clinical diversity of PK deficiency, the current standard of treatment, and for supportive care, disease complications, and future treatment directions.

The authors note the disease is underdiagnosed, that mildly affected individuals may be misdiagnosed, and that accurate diagnosis of the condition remains challenging, particularly in those without a detailed family history.

Find a link to the review article by Grace et al. on the Resources page.>

PK Deficiency Status Report

A 2015 article by Rachel Grace and colleagues2 reviews the clinical diversity of PK Deficiency, the current standard of treatment, and for supportive care, disease complications, and future treatment directions.

The authors note the disease is underdiagnosed, that mildly affected individuals may be misdiagnosed, and that accurate diagnosis of the condition remains challenging, particularly in those without a family history.

Find the review article by Grace et al. on the Resources page.>

Stay Informed: Sign up for updates from Agios

* Required Fields

By completing and submitting this form, you agree to allow Agios and its agents to collect the information provided and to contact you regarding its PK deficiency program and related disease information. Agios will not sell or otherwise share the information you provide other than with other companies or organizations acting as our agent to administer this website or to assist in providing the information you have requested.
Thank you for signing up!
We look forward to keeping you up-to-date on the latest news and offerings. We'll be in touch again soon.